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LPA contains multiple Kringle domains, including a hypervariable Kringle IV-type 2 region of ~5500 bp, which occurs in tandem from fewer than six copies to at least 40 times, and higher KIV-2 copy number generally associates with decreased Lp(a) protein abundance 15,16
In rodents, the enzyme long-chain acyl-CoA dehydrogenase (LCAD) can take over part of the VLCAD function, but in humans LCAD makes little contribution to lcFAO [6]
Johnson RR, Cranston HJ, Chaverra ME, Dyer WE (1995) Characterization of cDNA clones for differentially expressed genes in embryos of dormant and non-dormant Avenua fatua (L.) caryopses
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